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On Psychiatric ‘Signs’
Clinical assessments in psychiatric practice mostly rely on verbal report of symptoms by individuals who experience them. Some of these self- reports are corroborated by family members or other associates, providing information required to formulate the problem that...
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The Brain’s Relay Race to Remember
How do you transfer the password #498jOp_9@W4jjiLL from a paper to your screen? Have you ever wondered how your brain manages to keep information like a complicated password or an address in mind while you're typing it out? New work from a former NIMy group member...
Why Antipsychotics Don’t Work for Everyone
One group of people with schizophrenia seems to have too much of something called "glutamate" in a part of their brain called the frontal cortex. This group doesn't respond well to the usual first set of medicines psychiatrists usually give them, which act through...
Linguistic profiles in psychosis
From the whispered secrets of the mind to the untold stories that lie within, language remains our most potent tool for unravelling the mystery of schizophrenia. Drawing upon advancements in computational linguistics, Tyler Dalal, MD student at the Schulich explored...
Dopamine and substance use
Dopamine It is now well established that dopamine, a brain chemical, plays a crucial role in processing novelty, surprise and reward - all those thrilling and salient factors in everyday life. No wonder that dopamine levels may be aberrant in those who use...
Mostly intact brain structure in early psychosis
When psychosis first presents as a full blown episode, the symptoms are often severe and disabling. Over time, they reduce in frequency and intensity for many individuals. This pattern of severe symptoms in early stages, followed by reduced intensity over time, sets...
Opening Remarks at the Center of Excellence
These remarks were given by Dr. Palaniyappan when introducing the CEYMH at the Douglas Research Center to the audience at its inaugural seminar series on 20th April 2023 Good morning everyone. It is a pleasure to welcome you all and introduce the Centre of Excellence...
A special issue on a critical problem
Placing language at the centre of interest to understand and treat psychosis, a special issue of Schizophrenia Bulletin - the flagship journal in the field - was published on 22nd March 2023. It carries a set of 9 research papers and...
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The small bent beams and bridges of our brain
White matter bundles provide the beams and bridges that connect various parts of our brain. A special type of white matter is the one immediately below the surface of our brain. These structures, called 'U' fibers, are a group of short association fibers that connect...
On Psychiatric ‘Signs’
Clinical assessments in psychiatric practice mostly rely on verbal report of symptoms by individuals who experience them. Some of these self- reports are corroborated by family members or other associates, providing information required to formulate the problem that...
